研究方向：
1. 鸭精准营养、代谢与调控机制
研究不同养殖模式下鸭营养素精准需要、代谢规律及互作效应；研究饲料营养调控鸭肌肉发育和脂肪代谢的分子机制。
2. 鸭饲料营养价值评定
评价鸭饲料营养价值，研究饲料养分消化吸收和代谢利用特点及规律，解析鸭饲料养分高效利用的生物学特征及调控作用，阐明肠道微生物、饲料养分与肉鸭互作关系及调控机制。
3. 鸭肉风味物质形成机理及品质营养调控
鸭肉风味物质鉴定、形成规律和机理，优质鸭肉产品营养调控技术研究与应用。
代表性成果：
1. 肉鸭脂肪代谢营养调控技术创新
针对肉鸭规模化养殖过程脂肪沉积紊乱的问题，采用填饲方式和胆碱缺乏等构建肉鸭脂肪代谢障碍性疾病模型，通过表型测定、生理生化、多组学联合分析，筛选到肉鸭肝脏脂肪合成、转运和分解的关键基因和蛋白，明确肉鸭肝脏脂肪代谢的分子机制，并研发了以胆碱、蛋氨酸、核黄素、PUFA、磷脂、表面活性素等精准营养调控技术，相关研究结果发表文章12篇，制定《肉鸭饲养标准》1项
2. 代表性论文与专利
[1] Wu Y B, Tang J, Wen Z G*, et al. Dietary methionine deficiency stunts growth and increases fat deposition via deceleration of fatty acids transportation and hepatic catabolism in Pekin ducks. Journal of Animal Science and Biotechnology, 2022,13(1):61
[2] Liu J, Zhao L L, Wen Z G*, et al. Antioxidant and Anti-Inflammatory Properties of Rubber Seed Oil in Lipopolysaccharide-Induced RAW267.4 Macrophages. Nutrients, 2022, 14:1349.
[3] Cai H Y#, Wen Z G#, Yang P L, et al. Lactobacillus plantarum FRT4 alleviated obesity by modulating gut microbiota and liver metabolome in high-fat diet-induced obese mice. Food & Nutrition Research, 2022, 66: 7974
[4] Zhao L L, Cai H Y, Wu Y B, et al. Severe choline deficiency induces alternative splicing aberrance in optimized duck primary hepatocyte cultures. Animal Bioscience, 2022, doi: 10.5713/ab.22.0051.
[5] Liu J, Zhao L L, Zhao Z T, et al. Rubber (Hevea brasiliensis) seed oil supplementation attenuates immunological stress and inflammatory response in lipopolysaccharide-challenged laying hens. Poultry Science, 2022,101:102040.
[6] Zhang Y C, Si X M, Yang L, et al. Association between intestinal microbiota and inflammatory bowel disease. Animal Models and Experimental Medicine. 2022, accepted.
[7] Zhang Y C, Jiang D, Jin Y H, et al. Glycine Attenuates Citrobacter rodentium-Induced Colitis by Regulating ATF6-Mediated Endoplasmic Reticulum Stress in Mice. Molecular Nutrition ＆ Food Research. 2021,65(15):e2001065.
[8] Zhang Y C, Mu T Q, Yang Y, et al. Lactobacillus johnsonii Attenuates Citrobacter rodentium-Induced Colitis by Regulating Inflammatory Responses and Endoplasmic Reticulum Stress in Mice. Journal of Nutrition. 2021, 151(11):3391-3399.
[9] Wen Z G, Wu Y B, Yang P L*, et al. Rubber seed oil supplementation enriches n-3 polyunsaturated fatty acids and reduces cholesterol contents of egg yolks in laying hens. Food chemistry, 2019, 301:125198.
[10] Wu X Z, Yang P L, Wen Z G*, et al. Effect of dietary stevioside supplementation on growth performance, nutrient digestibility, serum parameters, and intestinal microflora in broilers. Food & Function, 2019, 10:2340-2346.
[11] Jing C L#, Wen Z G#, Zou P, et al. Consumption of Black Legumes Glycine soja and Glycine max Lowers Serum Lipids and Alters the Gut Microbiome Profile in Mice Fed a High-Fat Diet. Journal of Agricultural and Food Chemistry, 2018, 66(28):7367-7375.
[12] Wen Z G, T. J. Rasolofomanana, et al. Effects of dietary energy and lysine levels on growth performance and carcass yields of Pekin ducks from hatch to 21 days of age. Poultry Science, 2017, 96(9): 3361-3366.
[13]Wen Z. G, Du Y. K, Xie M, et al. Effects of low-protein diets on growth performance and carcass yields of growing French meat quails (France coturnix coturnix). Poultry Science, 2017, 96(5):1364-1369.
[14]Yong Jiang;Zhong Zhuang;Wenqia Jia;Zhiguo Wen;Ming Xie;Hao Bai;Yulin Bi;Zhixiu Wang;Guobin Chang;Shuisheng Hou;Guohong Chen. Proteomic and phosphoproteomic analysis reveal threonine deficiency increases hepatic lipid deposition in Pekin ducks via reducing STAT phosphorylation. Animal Nutrition.2023.
[15]Feng Y. Dai G. Han X. Li M. Zhao D. Wu J. Wu Y. Wen Z. Feeding Laying Ducks Eucommia ulmoides oliv. Leaves Increases the n-3 Fatty Acids Content and Decreases the n-6: n-3 PUFA Ratio in Egg Yolk without Affecting Laying Performance or Egg Quality. Foods.2023.
[16] 闻治国、赵璐璐、杨培龙、蔡红英、刘婧、吴永保、王帮磊. 鸭胚原代肝细胞分离培养方法.中国发明专利.申请日：2021.09.01，申请号：CN202111018025.0
[17] 闻治国、杨培龙、李秀梅、蔡红英、赵璐璐. 一种肉鸭低蛋白日粮及其应用.中国发明专利.申请日：2019.12.06，申请号：CN201911243146.8
[18] 闻治国、杨培龙、李秀梅、蔡红英、赵璐璐. 一种基于三层立体笼的肉鸭饲养方法.中国发明专利.申请日：2019.12.06，申请号：CN201911244673.0
[19] 闻治国、杨培龙、牛灿芳、李秀梅. 一种水禽自动饲喂装置. 中国实用新型专利.申请日：2017.03.29，授权日：2017.11.07，专号:ZL201720318761.0
[20] 闻治国；赵璐璐;杨培龙;蔡红英;刘婧;吴永保;王帮磊. 鸭胚原代肝细胞分离培养方法. ZL202111018025.0
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